EXPERIMENTAL URIC ACID NEPHRITIS IN THE RABBIT
| Autor: | Joseph F. Smith, Yin Chen Lee |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1957 |
| Předmět: |
Pathology
medicine.medical_specialty Immunology Kidney Article Lesion chemistry.chemical_compound Immunology and Allergy Medicine Animals Distal convoluted tubule Crush syndrome Kidney Tubules Distal Nephritis business.industry medicine.disease Uric Acid medicine.anatomical_structure chemistry Initial lesion Argument (complex analysis) Uric acid Rabbits medicine.symptom business |
| Zdroj: | The Journal of Experimental Medicine |
| ISSN: | 1540-9538 0022-1007 |
| Popis: | Experimental uric acid lesions in the kidney of the rabbit have been reinvestigated using the technique of miscrodissection for location of lesions. The maximal initial lesion was found to occur in the first part of the collecting, and not in the ascending Henle and the distal convoluted tubule. Such lesions were only produced by very high dosage (approximately 0.5–1 gm. per kg.). It was concluded that the argument by analogy with the uric acid lesion cannot be used to support a hypothetical toxic damage to the segments of ascending Henle and the distal convolution in the crush syndrome. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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