Assessing the Association of Surface-Intermediate-Base Margin Score with Perioperative Outcomes and Parenchymal Volume Preserved during Partial Nephrectomy
| Autor: | Hakan Bahadir Haberal, Burak Citamak, Bulent Akdogan |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Surgical margin Multivariate analysis Urology medicine.medical_treatment 030232 urology & nephrology Renal function Kidney Nephrectomy 03 medical and health sciences 0302 clinical medicine Renal cell carcinoma medicine Humans Prospective Studies Prospective cohort study Carcinoma Renal Cell Pathological Aged Aged 80 and over business.industry Margins of Excision Organ Size Perioperative Middle Aged medicine.disease Kidney Neoplasms Treatment Outcome 030220 oncology & carcinogenesis Female business Organ Sparing Treatments |
| Zdroj: | Urologia Internationalis. 104:781-788 |
| ISSN: | 1423-0399 0042-1138 |
| Popis: | Introduction: The present study aimed to compare the assessment of volume preservation and perioperative outcomes during partial nephrectomy (PN), according to the surface-intermediate-base (SIB) score. Methods: This prospective study included 80 patients diagnosed with renal cell carcinoma who underwent PN for a renal mass from 2014 to 2017. SIB score was macroscopically evaluated immediately after the surgery. Preoperative assessment of volume preservation (PAVP), surgeon assessment of volume preservation (SAVP), duration of ischemia, perioperative complications, pathological data, and the values of preoperative and postoperative estimated glomerular filtration rate (eGFR) were recorded. Results: A strong correlation was determined between PAVP and SAVP (R = 0.82, R2 = 0.68, p < 0.0001) and between vGFR-PAVP and vGFR-SAVP calculated using the adapted eGFR (preop eGFR × [PAVP or SAVP]) (R = 0.97, R2 = 0.95, p < 0.001). In multivariate analysis, preoperative tumor size, SIB score (1–2 vs. 3–5), and vGFR (PAVP and SAVP model) were significant predictors of postoperative eGFR. A low base score was associated with surgical margin positivity, and a high SIB score (≥3) was associated with perioperative complications (p = 0.017; p = 0.028). Conclusion: The SIB score can be considered a reliable surrogate for volume preservation after PN because it is strongly associated with both PAVP and SAVP. SIB score is useful in predicting functional outcomes, complications, and surgical margin positivity. |
| Databáze: | OpenAIRE |
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