Symmetry of disciform scars in bilateral age-related macular degeneration
| Autor: | M J Lavin, Z J Gregor, B Eldem |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1991 |
| Předmět: |
Male
medicine.medical_specialty Time Factors genetic structures Eye disease Scars Cellular and Molecular Neuroscience Cicatrix Macular Degeneration Risk Factors Age related Ophthalmology Medicine Humans Macula Lutea Macular scar Aged Retrospective Studies Aged 80 and over Retina Neovascularization Pathologic business.industry Macular degeneration Middle Aged medicine.disease Prognosis Sensory Systems eye diseases Surgery medicine.anatomical_structure Maculopathy Female sense organs medicine.symptom business Retinopathy Research Article |
| Popis: | The size of the final macular scar in subretinal neovascularisation (SRNV) is one of the most important determinants of final visual function in patients with subfoveal disease. We studied patients with bilateral macular scars from age-related subretinal neovascular membranes retrospectively in order to determine whether or not fellow eyes behave similarly. We found a significant correlation between eyes in terms of final scar size (r = 0.50, p less than 0.01). We found that 50% of fellow eyes with large macular scars (greater than 3 x 10(6) microns2) had similar sized lesions, while only 16% of fellow eyes with small macular scars (less than 0.5 x 10(6) microns2) had large scars (p less than 0.01). We discuss the significance of these findings in relation to the pathogenesis of subretinal neovascular membranes, and their implications for treatment. |
| Databáze: | OpenAIRE |
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