Complex autonomic dysfunction in cardiovascular, intensive care, and schizophrenic patients assessed by autonomic information flow
| Autor: | Pere Caminal, Montserrat Vallverdú, Christine Götze, Karl-Jürgen Bär, Daniel Hoyer, Phyllis K. Stein, Jan J. Zebrowski, Hendrik Schmidt, Rafał Baranowski, K. Falkenhahn, Birgit Frank, Bayés De Luna A |
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| Rok vydání: | 2006 |
| Předmět: |
Male
medicine.medical_specialty Critical Care Multiple Organ Failure Biomedical Engineering Information Storage and Retrieval Autonomic Nervous System Electrocardiography Biological Clocks Heart Rate medicine.artery Internal medicine Intensive care Idiopathic dilated cardiomyopathy medicine Humans Heart rate variability Diagnosis Computer-Assisted Intensive care medicine Heart Failure business.industry Abdominal aorta medicine.disease Pathophysiology Autonomic Nervous System Diseases Schizophrenia Heart failure Cardiology Multiple organ dysfunction syndrome business |
| Zdroj: | Biomedizinische Technik/Biomedical Engineering. 51:182-185 |
| ISSN: | 1862-278X 0013-5585 |
| Popis: | BACKGROUND The cardiovascular control system is mediated by mechanisms acting at different time scales, such as heart period, vagal, sympathetic, and other slower controllers. Since these elements are interrelated in a complex manner, classical control theory fails and information-based description, based on autonomic information flow (AIF) functions, is appropriate. We investigated the hypothesis that AIF functions of typical time scales specifically characterize autonomic dysfunction and prognosis. MATERIALS AND METHODS Holter recordings of patients with multiple organ dysfunction syndrome (MODS) (26 survivors, 10 non-survivors), heart failure (13 low risk, 13 high risk of cardiac arrest), idiopathic dilated cardiomyopathy (IDC) (26 low risk, 11 high risk), after abdominal aorta surgery (AAS) [32 with length of stay in hospital (LOS) >7 days; 62 with LOS < or =7 days] or with schizophrenia (n=20) were assessed and compared to 20 control subjects. RESULTS We found different AIF time scales discriminating risk. AIF measures of heart beat period had predominant prognostic value in heart failure patients, those of vagal communication in MODS and IDC, and those of long-term communication after AAS. Schizophrenic patients were discriminated from controls by vagally mediated communication. CONCLUSION Different time scales of AIF represent specific pathophysiological aspects of altered complex autonomic control (communication) and consequently have predictive implications. |
| Databáze: | OpenAIRE |
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