Sarcopenia in cardiac surgery: Dual X-ray absorptiometry study from the McGill frailty registry
| Autor: | Gad Abikhzer, Jean-Francois Morin, Lawrence G. Rudski, Aayushi Joshi, Rita Mancini, Jonathan Afilalo, Yves Langlois, Stephan Probst |
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| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Canada Sarcopenia Prevalence 030204 cardiovascular system & hematology 03 medical and health sciences Coronary artery bypass surgery 0302 clinical medicine Absorptiometry Photon Predictive Value of Tests Internal medicine Medicine Humans 030212 general & internal medicine Muscle Strength Registries Cardiac Surgical Procedures Mortality Correlation of Data Survival rate Geriatric Assessment Aged biology Frailty business.industry Hazard ratio Ammi Physical Functional Performance biology.organism_classification medicine.disease 3. Good health Cardiac surgery Lower Extremity Cohort Body Composition Female Cardiology and Cardiovascular Medicine business human activities |
| Zdroj: | American heart journal. 239 |
| ISSN: | 1097-6744 |
| Popis: | Background To determine the prevalence and prognostic value of sarcopenia measured by dual x-ray absorptiometry (DXA) and physical performance tests in patients undergoing coronary artery bypass surgery or heart valve procedures. Methods Adults undergoing cardiac surgery were prospectively enrolled and completed a questionnaire, physical performance battery, and a DXA scan (GE Lunar) to measure appendicular muscle mass indexed to height 2 (AMMI). Patients were categorized as sarcopenic based on European Working Group 2 guidelines if they had low AMMI defined as Results The cohort consisted of 141 patients with a mean age of 69.7 ± 10.0 years and 21% females. The prevalence rates of low AMMI, slow chair rise time, and sarcopenia (low AMMI and slow chair rise time) were 24%, 57%, 13%, respectively. The 4-year survival rate was 79% in the non-sarcopenic group as compared to 56% in the sarcopenic group (Log-rank P = 0.01). In the multivariable model, each standard deviation of decreasing AMMI and increasing chair rise time was associated with a hazard ratio for all-cause mortality of 1.84 (95% CI 1.18, 2.86) and 1.79 (95% CI 1.26, 2.54), respectively. Conclusion Lower-extremity muscle strength and DXA-based muscle mass are objective indicators of sarcopenia that are independently predictive of all-cause mortality in older cardiac surgery patients. |
| Databáze: | OpenAIRE |
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