Advanced Fine-Tuning of Grubbs/Hoveyda Olefin Metathesis Catalysts: A Further Step toward an Optimum Balance between Antinomic Properties

Autor:	Michal Bieniek, Guy Lavigne, Noël Lugan, Dieter Arlt, Robert Bujok, Karol Grela, Maciej Cabaj
Rok vydání:	2006
Předmět:	Olefin fiber Ligand Ether General Medicine General Chemistry Metathesis Biochemistry Combinatorial chemistry Catalysis chemistry.chemical_compound End-group Colloid and Surface Chemistry chemistry Yield (chemistry) Salt metathesis reaction Organic chemistry Acrylonitrile
Zdroj:	Journal of the American Chemical Society. 128:13652-13653
ISSN:	1520-5126 0002-7863
Popis:	A 95% yield in the cross metathesis of acrylonitrile with a model olefin is achieved at 25 degrees C with only 3 mol % of the new air-stable ruthenium catalyst 1f shown in the enclosed structural diagram. Even more remarkable are the performances of its boosted version 1g incorporating an electron-withdrawing group. Both these new enhanced versions of Hoveyda catalyst are readily available from Grubbs second generation precatalyst upon reaction with a styrenyl ether the end group of which has been functionalized by an ester function. The latter acts as a weakly coordinating ligand allowing to reach a desirable balance between antinomic properties such as the catalyst's stability, a high activity for challenging substrates, and a high initiation rate.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6b1d50cda43dfd837450d35fe9cb8f9 https://doi.org/10.1021/ja063186w Zobrazit plný text záznamu