Inducing targeted failure in cadaveric testing of 3-segment spinal units with and without simulated metastases
| Autor: | Esther Tanck, Yvette M. van der Linden, Jasper Johan Homminga, Karlijn H. J. Groenen, Nico Verdonschot, Dennis Janssen, Jan G. M. Kooloos |
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| Přispěvatelé: | Biomechanical Engineering |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Male
0206 medical engineering Vertebral strength Biomedical Engineering Biophysics Other Research Donders Center for Medical Neuroscience [Radboudumc 0] Computed tomography 02 engineering and technology Metastases 03 medical and health sciences 0302 clinical medicine Axial compression Materials Testing Cadaver Humans Medicine Aged Mechanical Phenomena Aged 80 and over medicine.diagnostic_test business.industry Mechanical testing Middle Aged 020601 biomedical engineering Spine Deformation Biomechanical Phenomena Vertebra Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10] medicine.anatomical_structure Fracture 2023 OA procedure Female business Cadaveric spasm Nuclear medicine Failure criterion 030217 neurology & neurosurgery |
| Zdroj: | Medical engineering & physics, 51, 104-110. Elsevier Medical Engineering and Physics, 51, 104-110 Medical Engineering & Physics, 51, pp. 104-110 Medical Engineering & Physics, 51, 104-110 |
| ISSN: | 1350-4533 |
| Popis: | Item does not contain fulltext We propose an experimental setup and protocol able to induce targeted failure of the middle vertebra in 3-segment spinal units and to capture the specimens' deformation in their post-failure state. Sixteen 3-segment spinal units with and without artificial metastases were destructively tested in axial compression using one of two failure criteria; either: (A) A clear drop in force (>10-15% of peak force) (n=4); or (B) A minimum displacement of 5mm (n=12). Subsequently, the specimens were fully fixated in polymethylmethacrylate (PMMA), thereby preserving their post-failure state. Pre- and post-experiment computed tomography (CT) scans were acquired to determine the occurrence of failure in one of the vertebral bodies. All specimens were successfully fixated in their post-failure state. When applying failure criterion A, two specimens showed signs of failure. When applying failure criterion B, all specimens showed signs of failure; in 9 out of 12 specimens this occurred in the middle vertebrae only. In conclusion, this research provides an experimental setup and protocol able to induce targeted failure of 3-segment spinal units and to capture the specimens' deformation in their post-failure state. Furthermore, this study illustrates the importance of an adequate failure criterion for successful simulation of vertebral fractures in an experimental setup. |
| Databáze: | OpenAIRE |
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