Oral Human Papillomavirus (HPV) Infection among Unvaccinated High-Risk Young Adults
| Autor: | Gypsyamber D'Souza, Emily E. Stammer, Renee M. Youngfellow, Nicole Kluz, Anne M. Griffioen, Yingshi Guo, Weihong Xiao, Maura L. Gillison, Alicia Wentz |
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| Rok vydání: | 2014 |
| Předmět: |
young adults
Cancer Research medicine.medical_specialty Multivariate analysis STD clinic lcsh:RC254-282 Article oral HPV gender Oral sex Internal medicine Medicine Oral hpv Human papillomavirus Young adult Gynecology business.industry HPV infection Cancer lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens medicine.disease stomatognathic diseases Hpv testing Oncology business |
| Zdroj: | Cancers; Volume 6; Issue 3; Pages: 1691-1704 Cancers Cancers, Vol 6, Iss 3, Pp 1691-1704 (2014) |
| ISSN: | 2072-6694 |
| DOI: | 10.3390/cancers6031691 |
| Popis: | Oral HPV infection, the cause of most oropharyngeal cancer in the U.S., is not well studied among high-risk young adults. Men (n = 340) and women (n = 270) aged 18–25 years attending Baltimore County STD clinics were recruited if they declined HPV vaccination. Each participant had a 30-second oral rinse and gargle sample tested for 37 types of HPV DNA, and a risk-factor survey. Factors associated with prevalent infection were explored using log binomial regression. Men had higher prevalence of any oral HPV (15.3% vs. 7.8%, p = 0.004) and vaccine-type oral HPV (i.e., HPV16/18/6/11: 5.0% vs. 1.1%, p = 0.007) infection than women. In multivariate analysis, male gender (aPR = 1.93, 95% CI = 1.10–3.39), number of recent oral sex partners (p-trend = 0.013) and having ever performed oral sex on a woman (aPR = 1.73, 95% CI = 1.06–2.82) were associated with increased oral HPV prevalence. Performing oral sex on a woman may confer higher risk of oral HPV acquisition than performing oral sex on a man. |
| Databáze: | OpenAIRE |
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