Severe Toxicity to the New Psychoactive Substances 3-Hydroxyphencyclidine and N-Ethylhexedrone: an Analytically Confirmed Case Report
| Autor: | Lisa Christine Dunlop, John R. H. Archer, Simon Hudson, David M. Wood, Paul I. Dargan |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Cathinone
biology Sinus tachycardia business.industry Health Toxicology and Mutagenesis Case Report 030208 emergency & critical care medicine Emergency department Toxicology medicine.disease Acute toxicity 03 medical and health sciences 0302 clinical medicine Anesthesia Toxicity medicine biology.protein Creatine kinase 030212 general & internal medicine medicine.symptom business Rhabdomyolysis Phencyclidine medicine.drug |
| Zdroj: | J Med Toxicol |
| ISSN: | 1937-6995 1556-9039 |
| DOI: | 10.1007/s13181-019-00734-x |
| Popis: | INTRODUCTION: 3-Hydroxyphencyclidine (3-HO-PCP) is a new psychoactive substance (NPS) and a hydroxy derivative of phencyclidine (PCP), and N-ethylhexedrone (Hexen) is a synthetic cathinone. We describe an analytically confirmed case of acute toxicity related to the use of both 3-hydroxyphencyclidine and N-ethylhexedrone. CASE REPORT: A 56-year-old male was brought to the Emergency Department by ambulance with hyperthermia (39.9 °C), sinus tachycardia (150 beats per minute), reduced consciousness, ocular clonus, and vertical nystagmus. He was treated with cooled intravenous (IV) fluids and IV benzodiazepines. Following 1 hour of treatment, his temperature fell to 37.7 °C, he developed rhabdomyolysis (creatine kinase peaked at 5999 IU (normal range |
| Databáze: | OpenAIRE |
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