Solid-phase synthesis of molecularly imprinted nanoparticles for protein recognition
| Autor: | Karsten Haupt, Serena Ambrosini, Bernadette Tse Sum Bui, Selim Beyazit |
|---|---|
| Přispěvatelé: | Génie Enzymatique et Cellulaire (GEC), Université de Technologie de Compiègne (UTC)-Université de Picardie Jules Verne (UPJV)-Centre National de la Recherche Scientifique (CNRS) |
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
inorganic chemicals
education Nanoparticle 02 engineering and technology 010402 general chemistry 01 natural sciences Catalysis Molecular Imprinting Solid-phase synthesis mental disorders Materials Chemistry Protein recognition medicine Organic chemistry Trypsin Solid-Phase Synthesis Techniques health care economics and organizations Chemistry Metals and Alloys Molecularly imprinted polymer technology industry and agriculture General Chemistry respiratory system 021001 nanoscience & nanotechnology Combinatorial chemistry 0104 chemical sciences 3. Good health Surfaces Coatings and Films Electronic Optical and Magnetic Materials Synthetic antibody Ceramics and Composites Nanoparticles Adsorption 0210 nano-technology Selectivity medicine.drug |
| Zdroj: | Chemical Communications Chemical Communications, Royal Society of Chemistry, 2013, 49, pp.6746-6748 |
| ISSN: | 1359-7345 1364-548X |
| Popis: | International audience; A solid-phase synthesis approach to prepare molecularly imprinted polymer nanoparticles (MIP-NPs) specific for trypsin is described. The protein is immobilized on a solid support upon which thermoresponsive MIP-NPs are synthesized. The MIP-NPs are released by a simple temperature change, resulting in synthetic antibody mimics exhibiting high specificity and selectivity for trypsin. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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