The recurrence of intracranial meningiomas after surgical treatment
| Autor: | Moe Khan, Andrew B. Adegbite, Leonard Tan, Kenneth W. E. Paine |
|---|---|
| Rok vydání: | 1983 |
| Předmět: |
Adult
Male medicine.medical_specialty Aging Time Factors Adolescent Decompression medicine.medical_treatment Brain tumor Sex Factors Histological diagnosis medicine Humans Postoperative Period Surgical treatment Child Survival analysis Aged Retrospective Studies business.industry Brain Neoplasms Infant Newborn Infant Retrospective cohort study Histology Middle Aged medicine.disease Surgery Radiation therapy Child Preschool Female Neoplasm Recurrence Local business Meningioma |
| Zdroj: | Journal of neurosurgery. 58(1) |
| ISSN: | 0022-3085 |
| Popis: | ✓ A study of 114 surgically treated patients with intracranial meningiomas was carried out to evaluate factors influencing recurrence. The date of the initial surgery extended over a 24-year period from January, 1956, to December, 1979. The patients ranged in age from 1½ years to 82 years. Seventy-one (62.3%) were females and 43 (37.7%) were males. The surgical procedure was graded according to Simpson's classification from 1 to 5 (Grade 1 = complete excision, Grade 5 = simple decompression). In this series, 33 procedures (28.9%) were Grade 1, 55 (48.2%) were Grade 2, seven (6.1%) were Grade 3, 18 (15.8%) were Grade 4, and one (0.9%) was Grade 5. There were eight (7%) postoperative deaths. Approximately 60% of the tumors were located in the sphenoid wing (23.7%), convexity (21.1%), and parasagittally (14.9%). Histological diagnosis in 96% of the patients was transitional (42.1%), syncytial (34.2%), and fibroblastic (20.2%) meningiomas. Eight (7%) patients received postoperative radiotherapy. There was evidence of recurrence in 22 patients (19.3%). Twenty-one underwent a second surgical procedure. Using survival analysis, it was determined that 80% of the patients were free of recurrence 5 years after the initial surgery, and approximately 50% showed no recurrence 20 years after the initial surgery. Only the grade of the initial surgery had a statistically significant influence on recurrence. Sex of patients, site and histology of the tumor, and postoperative radiotherapy had no statistically significant influence on recurrence. Angioblastic and malignant meningiomas were rare (only four cases), and recurred relatively quickly. |
| Databáze: | OpenAIRE |
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