Different neural circuits subserve reading before and after therapy for acquired dyslexia
| Autor: | Douglas C. Noll, Steven L. Small, Diane Kendall Flores |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Adult
Linguistics and Language Cognitive Neuroscience media_common.quotation_subject Experimental and Cognitive Psychology Speech Therapy Language and Linguistics Brain Ischemia Speech and Hearing Neuroimaging Communication disorder Reading (process) medicine Humans Language disorder media_common Dyslexia Acquired medicine.diagnostic_test Dyslexia Brain medicine.disease Magnetic Resonance Imaging Phonological dyslexia Reading Female Nerve Net Functional magnetic resonance imaging Psychology Occipital lobe Neuroscience |
| Zdroj: | Brain and language. 62(2) |
| ISSN: | 0093-934X |
| Popis: | Rehabilitative measures for stroke are not generally based on basic neurobiological principles, despite evidence from animal models that certain anatomical and pharmacological changes correlate with recovery. In this report, we use functional magnetic resonance imaging (fMRI) to study in vivo human brain reorganization in a right handed patient with an acquired reading disorder from stroke. With phonological dyslexia, her whole-word (lexical) reading approach included inability to read nonwords and poor reading of function words. Following therapy, she was able to read nonwords and function words, and preferred a decompositional (sub-lexical) strategy in general. fMRI was performed during a reading task before and after treatment. Prior to therapy, her main focus of brain activation was in the left angular gyrus (area 39). After therapy, it was instead in the left lingual gyrus (area 18). This result suggests first that it is possible to alter brain physiology with therapy for acquired language disorders, and second, that two reading strategies commonly used in normal reading use distinct neural circuits, possibly reconciling several conflicting neuroimaging studies of reading. |
| Databáze: | OpenAIRE |
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