Self-Assembly of Small Peptidomimetic Cyclophanes
| Autor: | M. Isabel Burguete, Gabriel Peris, Francisco Galindo, Juan F. Miravet, Jorge Becerril, Santiago V. Luis, Beatriu Escuder, Raquel Gavara |
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| Rok vydání: | 2004 |
| Předmět: |
Models
Molecular Circular dichroism Chemistry Peptidomimetic Circular Dichroism Molecular Mimicry Organic Chemistry Molecular Conformation Supramolecular chemistry General Chemistry Nuclear magnetic resonance spectroscopy Catalysis Crystallography X-Ray Diffraction Ethers Cyclic X-ray crystallography Microscopy Microscopy Electron Scanning Molecule Self-assembly Peptides Gels |
| Zdroj: | Chemistry - A European Journal. 10:3879-3890 |
| ISSN: | 1521-3765 0947-6539 |
| DOI: | 10.1002/chem.200400031 |
| Popis: | The self-assembly of a series of small peptidomimetic cyclophanes in organic solvents was studied. X-ray diffraction, NMR spectroscopy, and molecular modelling were used to understand the structural features of these self-assembling compounds both at the molecular and supramolecular level. The factors that could influence the formation of gels rather than crystals were studied and a model for the arrangement of molecules in the gel was proposed. Furthermore, scanning electron microscopy revealed that in some cases these compounds undergo a transcription of chirality when going from organogelator to helicoidal gel fibres. |
| Databáze: | OpenAIRE |
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