Quantified small bowel motility in patients with ulcerative colitis and gastrointestinal symptoms: a pilot study
| Autor: | Peter Leander, Julia Dreja, Olle Ekberg, Hanna Tufvesson, Sven Månsson, Bodil Ohlsson |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Motility Pilot Projects Ileum Disease Gastroenterology Jejunum Young Adult 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans Radiology Nuclear Medicine and imaging In patient Radiological and Ultrasound Technology medicine.diagnostic_test business.industry Magnetic resonance imaging General Medicine Middle Aged medicine.disease Magnetic Resonance Imaging Ulcerative colitis Small intestine Cross-Sectional Studies medicine.anatomical_structure Case-Control Studies 030220 oncology & carcinogenesis Colitis Ulcerative Female 030211 gastroenterology & hepatology Gastrointestinal Motility business |
| Zdroj: | Acta Radiologica. 62:858-866 |
| ISSN: | 1600-0455 0284-1851 |
| DOI: | 10.1177/0284185120946713 |
| Popis: | Background Gastrointestinal (GI) symptoms are common in patients with ulcerative colitis (UC), even when the disease is in remission, possibly due to abnormalities in GI motility. Small bowel motility can be assessed globally and in specific intestinal regions during magnetic resonance enterography (MRE) using a displacement mapping technique. Purpose To investigate whether small bowel motility in MRE differs between patients with UC and controls, and if altered motility correlates with GI symptoms. Material and Methods In 2016–2018, patients who were admitted for MRE, regardless of clinical indication, were consecutively invited to the study. Healthy volunteers were recruited. The participants completed a questionnaire regarding GI symptoms and relevant clinical data were reviewed in the medical records. The dynamic imaging series obtained during MRE were sent for motility mapping and a motility index (MI) was calculated in jejunum, ileum and terminal ileum in all participants. Results In total, 224 patients and healthy volunteers were enrolled in the study. Fifteen were diagnosed with UC and 22 were considered healthy controls. In UC, the prevalence of GI symptoms was higher than in controls ( P Conclusion Jejunal motility is decreased in UC compared with healthy controls, but there is no relationship between small bowel motility and GI symptoms in UC. |
| Databáze: | OpenAIRE |
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