A Population-Based Study of the Epidemiology of Pancreatic Cancer: A Brief Report
| Autor: | Maureen E. Trudeau, Joan Porter, William K. Evans, Ning Liu, Natalie G. Coburn, Matthew C. Cheung, N. Goyert, R. S. Raju, Jeffrey S Hoch, Katie N. Dainty, Craig C. Earle, Natasha B. Leighl, Nicole Mittmann, Soo Jin Seung |
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| Rok vydání: | 2015 |
| Předmět: |
Gerontology
medicine.medical_specialty Oncology and Carcinogenesis Population outcomes Pancreatic Cancer Rare Diseases Pancreatic cancer Epidemiology medicine Oncology & Carcinogenesis Aetiology education Cancer education.field_of_study business.industry Prevention Incidence (epidemiology) population studies retrospective analyses medicine.disease Comorbidity Cancer registry Good Health and Well Being Cohort Original Article Residence Digestive Diseases business Pancreatic adenocarcinoma 2.4 Surveillance and distribution Demography |
| Zdroj: | Raju, RS; Coburn, NG; Liu, N; Porter, JM; Seung, SJ; Cheung, MC; et al.(2015). A population-based study of the epidemiology of pancreatic cancer: A brief report. Current Oncology, 22(6), e478-e484. doi: 10.3747/co.22.2653. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/4bb7h2b1 Current oncology (Toronto, Ont.), vol 22, iss 6 Current Oncology Volume 22 Issue 6 Pages 2653-484 |
| ISSN: | 1718-7729 |
| DOI: | 10.3747/co.22.2653 |
| Popis: | Administrative data are used to describe the pancreatic cancer (pcc) population. The analysis examines demographic details, incidence, site, survival, and factors influencing mortality in a cohort of individuals diagnosed with pcc. Incident cases of pcc diagnosed in Ontario between 1 January 2004 and 31 December 2011 were extracted from the Ontario Cancer Registry. They were linked by encrypted health card number to several administrative databases to obtain demographic and mortality information. Descriptive, bivariate, and survival analyses were conducted. During the period of interest, 9221 new cases of pcc (4548 in men, 4673 in women) were diagnosed, for an age-adjusted standardized annual incidence in the range of 8.6&ndash 9.5 per 100,000 population. Mean age at diagnosis was 70.3 ± 12.5 years (standard deviation). Five-year survival was 7.2% (12.8% for those 80 years of age). Survival varied by sex, older age, rural residence, lower income, site of involvement in the pancreas, and presence of comorbidity. The mortality rate in pcc is exceptionally high. With an increasing incidence and a mortality positively associated with age, additional support will be needed for this highly fatal disease as demographics in Ontario continue to trend toward a higher proportion of older individuals. |
| Databáze: | OpenAIRE |
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