Innervation of heart cells in culture by an endogenous source of cholinergic neurons
| Autor: | Antonio Sastre, Mary-Ann Lane, Miriam M. Salpeter |
|---|---|
| Rok vydání: | 1976 |
| Předmět: |
medicine.medical_specialty
Carbachol Epinephrine Neuromuscular Junction Endogeny Tetrodotoxin Biology Neuromuscular junction Membrane Potentials Mice Norepinephrine chemistry.chemical_compound Heart Rate Parasympathetic Nervous System Internal medicine medicine Animals Cholinergic neuron Cells Cultured Multidisciplinary Myocardium Heart Receptors Muscarinic Embryonic stem cell Cell biology Microscopy Electron medicine.anatomical_structure Endocrinology nervous system chemistry Cell culture Cholinergic Research Article medicine.drug |
| Zdroj: | Proceedings of the National Academy of Sciences. 73:4506-4510 |
| ISSN: | 1091-6490 0027-8424 |
| DOI: | 10.1073/pnas.73.12.4506 |
| Popis: | Hearts of embryonic mice 9 days in utero were found to have an endogenous source of cholinergic neurons which can survive in dispersed cell cultures. These neurons are electrically excitable, have ultrastructural characteristics of cholinergic embryonic neurons, and functionally innervate heart cells in culture. The nature of the innervation described is muscarinic cholinergic. |
| Databáze: | OpenAIRE |
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