Zebrafish heart regeneration as a model for cardiac tissue repair

Autor:	Robert J. Major, Kenneth D. Poss
Rok vydání:	2007
Předmět:	Future studies biology Heart disease Regeneration (biology) Tissue repair Bioinformatics biology.organism_classification medicine.disease Article Drug Discovery medicine Molecular Medicine Limited capacity Zebrafish Organism
Zdroj:	Drug Discovery Today: Disease Models. 4:219-225
ISSN:	1740-6757
DOI:	10.1016/j.ddmod.2007.09.002
Popis:	Heart disease remains the leading cause of mortality throughout the world. Mammals have an extremely limited capacity to repair lost or damaged heart tissue, thus encouraging biologists to seek out models for heart regeneration. Zebrafish exhibit a robust regenerative capacity in a variety of tissues including the fin, spinal cord, retina, and heart, making it the sole regenerative vertebrate organism currently amenable to genetic manipulation. Future studies will utilize functional approaches to tease apart zebrafish heart regeneration in hopes of unlocking our own regenerative potential.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f678336b089d3a13d713a972d1a5b78d https://doi.org/10.1016/j.ddmod.2007.09.002 Zobrazit plný text záznamu Full Text from ScienceDirect