Dilated Optic Nerve Sheath in Mucopolysaccharidosis I: Common and Not Necessarily High Intracranial Pressure

Autor:	S. Huang, T. Lund, P. Orchard, A. Gupta, D. Nascene
Rok vydání:	2022
Předmět:	Radiology Nuclear Medicine and imaging Neurology (clinical)
Zdroj:	American Journal of Neuroradiology. 44:91-94
ISSN:	1936-959X 0195-6108
Popis:	Hydrocephalus is one of the earliest manifestations of mucopolysaccharidosis I-Hurler syndrome, and delayed treatment of hydrocephalus can lead to neurocognitive delay or even death. Optic nerve sheath diameter has been established as a noninvasive measurement to detect elevated intracranial pressure. This study aimed to establish correlations between optic nerve sheath diameter and opening pressure. Forty-nine MR images and opening pressures in patients with mucopolysaccharidosis I-Hurler syndrome were retrospectively reviewed from 2008 to 2020. The optic nerve sheath diameter was measured 3 mm posterior to the posterior margin of the globe (retrobulbar) and 10 mm anterior to the optic foramen (midpoint segment), and the average was taken between the 2 eyes. Opening pressure was measured with the patient in the lateral decubitus position with controlled end-tidal CO
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f674aeadbb265717802f0ebd348f83b4 https://doi.org/10.3174/ajnr.a7755 Zobrazit plný text záznamu