Incidence and anatomy of cardiac malformations in children conceived by assisted reproduction techniques - A review
| Autor: | Nicole de Oliveira Bernardes, Gabriela Cristina de Araujo Lima, Ludmila Santos Coelho, Wanessa Dias Bruce, Paulo Franco Taitson, Daniela D. Kwong |
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| Rok vydání: | 2022 |
| Předmět: |
Infertility
medicine.medical_specialty education.field_of_study business.industry Incidence (epidemiology) media_common.quotation_subject Population Coarctation of the aorta medicine.disease Surgery Stenosis medicine.anatomical_structure cardiovascular system medicine Interventricular septum Reproduction education business Tetralogy of Fallot media_common |
| Zdroj: | JBRA assisted reproduction. 18(2) |
| ISSN: | 1518-0557 |
| Popis: | The aim of this study is to identify the occurrence of car- diac malformations occurred in children conceived by as- sisted reproduction techniques (ART) in the international literature in Medline database from 1999 to 2012. The search returned data on 32,000 births, whose 21,000 were conceived naturally and 11,000 were conceived by ICSI and/or IVF. The incidence of cardiac malformations in general population situations was 0.4%. The incidence of cardiac malformations by ART was 1.8% from ICSI and IVF. Among the situations of conceived naturally was observed 88 cases of cardiac malforma- tions, which were: Atrial Septal Defect: 26 cases 29.55%, Change in the interventricular septum: 18 cases 20.45%, coarctation of the aorta: 13 cases 14.77%, aortic stenosis: 11 cases 12.5%, tetralogy of Fallot: 5.68% 5 cases, steno- sis of the pulmonary trunk: 5 cases 5.68% other: 11.37% 10 cases. In cases of cardiac malformations in children conceived by IVF and ICSI, 198 cases were found, which were: CIA: 58 cases 29.30%, Change in the interventric- ular septum: 37 cases 18.69%, coarctation of the aorta: 20 cases 10.10%, aortic stenosis: 18 cases 9.09%, tetral- ogy of Fallot: 11 cases 5.55%, stenosis of the pulmonary trunk: 6 cases 3.03%, Other: 48 cases 24.24%. There remain opened questions about infertility and risk factors involving ART. Further research is clearly required. Health care providers should counsel infertile couples seeking as- sisted reproduction by IVF and technology. |
| Databáze: | OpenAIRE |
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