| Autor: |
Carlos Padilla, Omar Cáceres, Omar Trujillo, David Tarazona, Eduardo Tarazona-Santos, Wei Song, Amol C. Shetty, Cesar Sanchez, Michael D. Kessler, Heinner Guio, Harrison Montejo, Marco Galarza, Kelly S. Levano, Silvia Capristano, Daniel N. Harris, Victor Borda, Pedro O. Flores-Villanueva, Timothy D. O’Connor |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| DOI: |
10.1101/219808 |
| Popis: |
Native Americans from the Amazon, Andes, and coast regions of South America have a rich cultural heritage, but have been genetically understudied leading to gaps in our knowledge of their genomic architecture and demographic history. Here, we sequenced 150 high-coverage and genotyped 130 genomes from Native American and mestizo populations in Peru. A majority of our samples possess greater than 90% Native American ancestry and demographic modeling reveals, consistent with a rapid peopling model of the Americas, that most of Peru was peopled approximately 12,000 years ago. While the Native American populations possessed distinct ancestral divisions, the mestizo groups were admixtures of multiple Native American communities which occurred before and during the Inca Empire. The mestizo communities also show Spanish introgression only after Peruvian Independence. Thus, we present a detailed model of the evolutionary dynamics which impacted the genomes of modern day Peruvians. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
