The electrophysiological tests in the early detection of the visual pathway dysfunction in patients with microadenoma
| Autor: | Ewelina Lachowicz, Agnieszka Kaźmierczyk-Puchalska, Elzbieta Andrysiak-Mamos, Wojciech Gosławski, Anhelli Syrenicz, Wojciech Lubiński |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
genetic structures PERG Visual impairment Early detection Optic chiasm PVEP 01 natural sciences 03 medical and health sciences 0302 clinical medicine Physiology (medical) Ophthalmology Electroretinography medicine Visual pathway dysfunction Humans Visual Pathways In patient Original Research Article 0101 mathematics medicine.diagnostic_test Pituitary tumour business.industry 010102 general mathematics Microadenoma Magnetic resonance imaging MVEP eye diseases Sensory Systems Ganglion Electrophysiology Early Diagnosis medicine.anatomical_structure 030221 ophthalmology & optometry Optic nerve Evoked Potentials Visual Visual Field Tests sense organs medicine.symptom business Tomography Optical Coherence |
| Zdroj: | Documenta Ophthalmologica. Advances in Ophthalmology |
| ISSN: | 1573-2622 0012-4486 |
| DOI: | 10.1007/s10633-021-09827-x |
| Popis: | Purpose To evaluate the validity of electrophysiological tests in the early diagnosis of a ganglion cells and/or optic nerve dysfunction in patients with pituitary microadenoma. Methods 66 eyes, from 33 patients with microadenoma with no evidence of the optic chiasm compression in magnetic resonance imaging (MRI) and the visual impairment in the routine ophthalmological examination, standard static perimetry (24-2 white on white) and optical coherence tomography (HD-OCT), were analysed. The pattern electroretinogram (PERG), standard pattern visual evoked potentials (PVEPs) and multichannel visual evoked potentials (mVEPs) (ISCEV standards) were performed. The results obtained from the electrophysiological tests were compared to the same number of age-matched healthy controls. Results Statistically significant differences between the patients with microadenoma and healthy controls were detected in all electrophysiological tests (p Conclusions In patients with microadenoma, the abnormalities in the electrophysiological tests are registered even without clinical evidence of visual impairment from the routine ophthalmological examination, SAP, OCT and chiasmal compression in MRI. The mVEPs have the most significant role in the diagnosis of the visual pathway dysfunction in patients with microadenoma. |
| Databáze: | OpenAIRE |
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