Genome analysis of the platypus reveals unique signatures of evolution
| Autor: | Ross C. Hardison, Caleb Webber, Malcolm A. Ferguson-Smith, Camilla M. Whittington, Rosalind Attenborough, Jarret Glasscock, Yoko Sekita, Xiaoqiu Huang, Emily S. W. Wong, Kym Hallsworth-Pepin, Laura Clarke, Jan Ole Kriegs, Makedonka Mitreva, Willem Rens, Todd Wylie, Arian F.A. Smit, Paul D. Waters, Angelika Merkel, Anthony T. Papenfuss, Ewan Birney, Brett Nixon, Asif T. Chinwalla, Alexander Stark, Ravi Sachidanandam, Neil J. Gemmell, Thomas H. Pringle, Juergen Schmitz, Daniel McMillan, Hitoshi Niwa, Russell C. Jones, Pat Miethke, Lin Chen, Gennady Churakov, Scott M. Smith, Gregory J. Hannon, Doron Lancet, Tsviya Olender, John W. Wallis, Joanne O. Nelson, Gavin A. Huttley, Lucinda Fulton, Prathapan Thiru, Jennifer A. Marshall Graves, Manolis Kellis, Devin P. Locke, Michael N. Nhan, Amber E. Alsop, Yucheng Feng, Pouya Kheradpour, Shunfeng Hou, Frédéric Veyrunes, Jean Louis Dacheux, Andrew J Pask, Ze Cheng, Wesley C. Warren, Bob Fulton, Colin Kremitzki, Miriam K. Konkel, Marilyn B. Renfree, Carly Smith, Gonzalo R. Ordóñez, Richard K. Wilson, Patrick Minx, Webb Miller, Yuan Chen, Xose S. Puente, Evan E. Eichler, Chris P. Ponting, Christophe Lefevre, Craig Pohl, Juergen Brosius, Shiaw Pyng Yang, Tina Graves, Robert S. Harris, Matthew Wakefield, Jerilyn A. Walker, Katherine Thompson, Janine E. Deakin, Peter Temple-Smith, Chris Markovic, Elaine R. Mardis, Michael Kube, Patrick J. Kirby, David A. Ray, Andreas Heger, Katherine Belov, Richard Reinhardt, Elizabeth P. Murchison, Iris M. Vargas Jentzsch, Kevin R. Nicholas, James Taylor, Mark A. Batzer, Anja Zemann, Frank Grützner, Emmanuel Buschiazzo, Patricia Wohldmann, Carlos López-Otín, Julie A. Sharp, Paul Flicek, Kim D. Delehaunty, LaDeana W. Hillier, Enkhjargal Tsend-Ayush |
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| Přispěvatelé: | Genome Sequencing Center, University of Washington School of Medicine, Australian National University (ANU), The Wellcome Trust Sanger Institute [Cambridge], University of Oxford [Oxford], University of Adelaide, Faculty of Veterinary Science, The University of Sydney, Center for Comparative Genomics and Bioinformatics (CCBB), Pennsylvania State University (Penn State), Penn State System-Penn State System, Department of Veterinary Medicine, University of Cambridge [UK] (CAM), Instituto Universitario de Oncología, University of Washington [Seattle], University of Canberra, The Walter and Eliza Hall Institute of Medical Research (WEHI), Department of Molecular Genetics, Weizmann Institute of Science [Rehovot, Israël], University of Melbourne, Monash University, Louisiana State University (LSU), Penn State System, University of Sydney, University of Canterbury [Christchurch], University of Münster, University of Texas, West Virginia University, Max Planck Institute for Molecular Genetics (MPIMG), Max-Planck-Gesellschaft, Sperling Foundation, Partenaires INRAE, State University of New York (SUNY), University of Newcastle (UoN), Physiologie de la reproduction et des comportements [Nouzilly] (PRC), Institut National de la Recherche Agronomique (INRA)-Institut Français du Cheval et de l'Equitation [Saumur]-Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS), RIKEN Plant Science Center, Iowa State University (ISU), Massachusetts Institute of Technology (MIT), Institut National de la Recherche Agronomique (INRA)-Institut Français du Cheval et de l'Equitation [Saumur]-Université de Tours-Centre National de la Recherche Scientifique (CNRS) |
| Jazyk: | angličtina |
| Rok vydání: | 2008 |
| Předmět: |
Male
0106 biological sciences [SDV]Life Sciences [q-bio] Genomics Receptors Odorant Monotreme 010603 evolutionary biology 01 natural sciences Genome Article Evolution Molecular Genomic Imprinting 03 medical and health sciences Molecular evolution biology.animal parasitic diseases Animals Dentition Humans [INFO]Computer Science [cs] Platypus Platypus venom Gene Phylogeny Zona Pellucida Repetitive Sequences Nucleic Acid 030304 developmental biology Mammals Whole genome sequencing Genetics Base Composition 0303 health sciences Multidisciplinary biology Venoms Immunity Reptiles Sequence Analysis DNA Milk Proteins biology.organism_classification Spermatozoa ORNITHORYNQUE MicroRNAs Female |
| Zdroj: | Nature Nature, Nature Publishing Group, 2008, 453 (7192), pp.175-183. ⟨10.1038/nature06936⟩ |
| ISSN: | 1476-4687 0028-0836 1476-4679 |
| Popis: | International audience; We present a draft genome sequence of the platypus, Ornithorhynchus anatinus. This monotreme exhibits a fascinating combination of reptilian and mammalian characters. For example, platypuses have a coat of fur adapted to an aquatic lifestyle; platypus females lactate, yet lay eggs; and males are equipped with venom similar to that of reptiles. Analysis of the first monotreme genome aligned these features with genetic innovations. We find that reptile and platypus venom proteins have been co- opted independently from the same gene families; milk protein genes are conserved despite platypuses laying eggs; and immune gene family expansions are directly related to platypus biology. Expansions of protein, non- protein- coding RNA and microRNA families, as well as repeat elements, are identified. Sequencing of this genome now provides a valuable resource for deep mammalian comparative analyses, as well as for monotreme biology and conservation. |
| Databáze: | OpenAIRE |
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