Microbial production of short chain diols
| Autor: | Mo Xian, Ning Tian, Wei Liu, Yudong Jiang, Huibin Zou, Tao Cheng |
|---|---|
| Jazyk: | angličtina |
| Předmět: |
Microbial metabolism
Bioengineering Review Downstream technologies Applied Microbiology and Biotechnology Downstream (manufacturing) Bioenergy polycyclic compounds Butylene Glycols Bacteria integumentary system business.industry Chemistry Butanediol Propanediol Biotechnology Microbial synthesis Propylene Glycols Biofuel Scientific method Fermentation Fine chemical Biochemical engineering business Renewable resource |
| Zdroj: | Microbial Cell Factories |
| ISSN: | 1475-2859 |
| DOI: | 10.1186/s12934-014-0165-5 |
| Popis: | Short chain diols (propanediols, butanediols, pentanediols) have been widely used in bulk and fine chemical industries as fuels, solvents, polymer monomers and pharmaceutical precursors. The chemical production of short chain diols from fossil resources has been developed and optimized for decades. Consideration of the exhausting fossil resources and the increasing environment issues, the bio-based process to produce short chain diols is attracting interests. Currently, a variety of biotechnologies have been developed for the microbial production of the short chain diols from renewable feed-stocks. In order to efficiently produce bio-diols, the techniques like metabolically engineering the production strains, optimization of the fermentation processes, and integration of a reasonable downstream recovery processes have been thoroughly investigated. In this review, we summarized the recent development in the whole process of bio-diols production including substrate, microorganism, metabolic pathway, fermentation process and downstream process. Electronic supplementary material The online version of this article (doi:10.1186/s12934-014-0165-5) contains supplementary material, which is available to authorized users. |
| Databáze: | OpenAIRE |
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