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ARTYKIEWICZ, Klaudia, CZARKOWSKI, Marcin, GORCZYCA, Kamila, GRODKIEWICZ, Maria, KOZIEŁ, Paweł, KRZYSIEK, Urszula, PODGÓRSKA, Klaudia, PUŁA, Aleksandra, SŁUPCZYŃSKA, Aleksandra & URBAŚ, Weronika. Celiac disease - a review on recent advances in characteristics, diagnostic and treatments. Journal of Education, Health and Sport. 2023;13(1):11-17. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2023.13.01.001 https://apcz.umk.pl/JEHS/article/view/40835 https://zenodo.org/record/7348088 The journal has had 40 points in Ministry of Education and Science of Poland parametric evaluation. Annex to the announcement of the Minister of Education and Science of December 21, 2021. No. 32343. Has a Journal's Unique Identifier: 201159. Scientific disciplines assigned: Physical Culture Sciences (Field of Medical sciences and health sciences); Health Sciences (Field of Medical Sciences and Health Sciences). Punkty Ministerialne z 2019 - aktualny rok 40 punktów. Załącznik do komunikatu Ministra Edukacji i Nauki z dnia 21 grudnia 2021 r. Lp. 32343. Posiada Unikatowy Identyfikator Czasopisma: 201159. Przypisane dyscypliny naukowe: Nauki o kulturze fizycznej (Dziedzina nauk medycznych i nauk o zdrowiu); Nauki o zdrowiu (Dziedzina nauk medycznych i nauk o zdrowiu). © The Authors 2022; This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 02.11.2022. Revised: 20.11.2022. Accepted: 22.11.2022. Celiac disease- a review on recent advances in characteristics, diagnostic and treatments Klaudia Artykiewicz1 Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie https://orcid.org/0000-0003-2912-4691 e-mail:klaudiaartykiewicz@gmail.com Marcin Czarkowski2 Uniwersytet Medyczny w Lublinie https://orcid.org/0000-0001-5663-2574 e-mail: marcin.czarkowski98@gmail.com Kamila Gorczyca3 Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie https://orcid.org/0000-0002-7976-0509 e-mail: kamila.gorczyca@o2.pl Maria Grodkiewicz4 Uniwersytet Medyczny w Lublinie https://orcid.org/0000-0002-6243-9102 e-mail: marysiagrodkiewicz@gmail.com Paweł Kozieł5 Uniwersytet Medyczny w Lublinie https://orcid.org/0000-0001-6069-6028 e-mail: pawelkoziel61@gmail.com Urszula Krzysiek6 Szpital Solec Spółka z Ograniczoną Odpowiedzialnością w Warszawie https://orcid.org/0000-0002-4712-2334 e-mail: urszula.krzysiek@onet.eu Klaudia Podgórska7 Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie https://orcid.org/0000-0002-5109-900X e-mail: kpodgorska06@gmail.com Aleksandra Puła8 Wojewódzki Szpital Specjalistyczny im. Kardynała Stefana Wyszyńskiego SPOZ w Lublinie https://orcid.org/0000-0001-9001-5051 e-mail: aleksandrapula@gmail.com Aleksandra Słupczyńska9 Samodzielny Publiczny Szpital Kliniczny Nr 1 w Lublinie https://orcid.org/0000-0003-3615-002X e-mail: olaslup@gmail.com WeronikaUrbaś10 Uniwersytet Medyczny w Lublinie https://orcid.org/0000-0002-5260-2172 e-mail: weronikaurbass@gmail.com Autor korespondencyjny: Klaudia Artykiewicz Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie https://orcid.org/0000-0003-2912-4691 e-mail:klaudiaartykiewicz@gmail.com, Abstract Introduction and purpose: Celiac disease occurs in 1% of the general population. However, many cases remain unrecognized. The diseaseis a chronic immune-mediated disorder triggered by the ingestion of gluten that appears in individuals with genetic susceptibility. Celiac disease can develop in paediatric patients as well as adults. The purpose of this review is to analyze the newest information on the characteristics, diagnosis and treatment of patients with celiac disease. Material and methods: This review was based on available data collected in the PubMed database and published between 2015 and 2022. The research was done by looking through keywords such as: “celiac disease”, “Gluten-Free Diet”, “diagnosis” and “treatment”. Results: The diagnosis of celiac disease is most often delayed due to the broad spectrum of presentations. Screening of at-risk individuals is important to progress the diagnosis. It is additionally crucial to raise clinicians' attention to non-specific parenteral symptoms that may indicate celiac disease. The majority of the symptoms arise from nutritional deficiencies caused by intestinal malabsorption. According to scientific reports, the most common deficiencies of people with celiac disease are iron, folic acid, vitamin B12, fat-soluble vitamins and a calcium. Conclusions: Recent years have seen the emergence of research into new therapeutic options, but their efficacy and safety still need to be evaluated more thoroughly. Strict adherence to a gluten-free diet by patients is still the only treatment option at present. Celiac disease, due to the constant increase in knowledge about its pathogenesis, diagnosis and treatment is an important material for further research. Keywords: Celiac disease, Gluten-Free Diet, Diagnosis, Treatment |
