Coinfection of Human Immunodeficiency Virus-Infected Patients with Hepatitis B Virus in Lokoja, North Central Nigeria

Autor: Sunday Ocholi Samson, Charles Kehinde Mofolorunsho, Ndah Sumaila Akpala, David Moses Adaji, Joseph Abraham Oyiguh, Martin-Luther Oseni Okolo, Douye V. Zige, Cornelius Arome Omatola
Rok vydání: 2020
Předmět:
Zdroj: Viral Immunology. 33:391-395
ISSN: 1557-8976
0882-8245
DOI: 10.1089/vim.2019.0157
Popis: Globally, coinfection of human immunodeficiency virus (HIV) patients with Hepatitis B Virus (HBV) is associated with an accelerated progression of HIV disease and higher mortality resulting from complications of liver-related disease. Despite the public health importance, data are lacking on this subject in the study area. Therefore, we evaluated the prevalence and risk factors for HIV/HBV coinfection among HIV patients accessing antiretroviral treatment in Lokoja, Nigeria. In a cross-sectional study, sera from randomly selected 200 consenting HIV patients were screened for hepatitis B surface antigen (HBsAg) using The Commercial Rapid Immunoassay Test Kit. Demographic variables and putative risk factors of HBV transmission were obtained using structured questionnaire. HBsAg prevalence was 8.0% in the sampled group with higher seropositivity rate in the age group, 40-49 years, followed by those 20-29 years of age, whereas the other age groups had zero positivity rates each. The difference between seroprevalence rates in relation to patients' age and sex was not statistically significant (
Databáze: OpenAIRE