Comparison of interferon action in interferon resistant and sensitive L1210 cells
| Autor: | P. Vandenbussche, J. Content, B. Lebleu, J. Werenne |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Phosphatase
Stimulation Aminoacylation Biology RNA Transfer Amino Acyl Vesicular stomatitis Indiana virus Mice Interferon Leucine Virology medicine Animals Phosphorylation Leukemia L1210 Cell-Free System RNA Phosphoproteins Molecular biology Biochemistry Phosphoprotein Protein Biosynthesis L1210 cells Interferons medicine.drug |
| Zdroj: | The Journal of general virology. 41(1) |
| ISSN: | 0022-1317 |
| Popis: | Summary Translation inhibition, leu-tRNA aminoacylation and double-stranded RNA and ATP dependent phosphorylation were examined in interferon-treated and control cell-free lysates of leukaemic mouse L 1210 R and L 1210 S cells. No differences were observed between the respective interferon-treated and control cell-free extracts, except for the presence of an enhanced 67K dalton phosphoprotein fraction in interferon-treated L 1210 S cell-free extracts. In non-responding cell-free lysates, the lack of stimulation of a 67K dalton phosphoprotein fraction cannot be explained by the presence of an increased level of some inhibitory activity, such as a phosphatase. |
| Databáze: | OpenAIRE |
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