Renal prostaglandins
| Autor: | G R, Zins |
|---|---|
| Rok vydání: | 1975 |
| Předmět: |
Angiotensin II
Indomethacin Natriuresis Biological Transport Arachidonic Acids General Medicine Water-Electrolyte Balance Kidney Capillaries Diuresis Mixed Function Oxygenases Kidney Tubules Proximal Vasomotor System Alcohol Oxidoreductases Regional Blood Flow Hypertension Prostaglandins Animals Humans |
| Zdroj: | The American Journal of Medicine. 58:14-24 |
| ISSN: | 0002-9343 |
| Popis: | Relative renal ischemia, produced by a variety of interventions, is modulated or buffered by prostaglandins synthesized within the kidney. These prostaglandins, however, do not account for renal autoregulation in its classic sense. They can facilitate salt and water excretion, largely through effects on physical forces in proximal peritubular capillaries, as evidenced by augmented renal blood flow. Renal prostaglandins may play a role in chronic water balance, but they probably are not important in chronic electrolyte homeostasis. There are several potential mechanisms by which renal prostaglandins could exert antihypertensive efects. Establishment of the importance of these agents, however, as antihypertensive hormones remains a challenge for future investigation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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