Serum Glucose-To-Potassium Ratio as a Prognostic Predictor for Severe Traumatic Brain Injury
| Autor: | Ami, Shibata, Fumihiro, Matano, Nobuyuki, Saito, Yu, Fujiki, Hisashi, Matsumoto, Takayuki, Mizunari, Akio, Morita, Shibata, Ami, Matano, Fumihiro, Saito, Nobuyuki, Fujiki, Yu, Matsumoto, Hisashi, Mizunari, Takayuki, Morita, Akio |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Blood Glucose Male medicine.medical_specialty Adolescent Traumatic brain injury Severity of Illness Index Young Adult 03 medical and health sciences 0302 clinical medicine Predictive Value of Tests Internal medicine Brain Injuries Traumatic Female patient medicine Humans Aged Retrospective Studies Aged 80 and over business.industry Head injury General Medicine Odds ratio Middle Aged Prognosis medicine.disease Serum glucose 030220 oncology & carcinogenesis Hemorrhagic shock Potassium Female 030211 gastroenterology & hepatology business Biomarkers |
| Zdroj: | Journal of Nippon Medical School. 88:342-346 |
| ISSN: | 1347-3409 1345-4676 |
| DOI: | 10.1272/jnms.jnms.2021_88-506 |
| Popis: | BACKGROUND Initial management of severe traumatic brain injury is important and includes treatment decision-making and prediction of prognosis. We examined whether biomarkers at admission could be useful prognostic predictors. We focused on electrolytes and blood glucose, which can be measured easily at any facility and for which results can be obtained promptly, before those of other biomarkers, such as D-dimer. METHODS All trauma patients with head injuries treated at Chiba Hokusoh Hospital between 2014 and 2017 were investigated. Cases of multiple trauma accompanied by fatal trauma, hemorrhagic shock, or cardiopulmonary arrest, and pediatric cases, were excluded from this study. Blood gas data at the initial hospital visit were reviewed retrospectively. A poor outcome was defined as death during hospitalization or a vegetative state due to head injury. Factors related to poor outcomes were analyzed. RESULTS Of the 185 male and 79 female patients studied, 34 had poor outcomes. Poor outcome was significantly correlated with potassium (P = 0.003), glucose (P < 0.001), and glucose-to-potassium ratio (P < 0.001) at arrival. The odds ratio was 4.079 for a glucose-to-potassium ratio of ≥50. CONCLUSIONS We evaluated blood gas data at the initial hospital visit, as these results can be obtained more quickly than those of other biomarkers assessed previously. Serum glucose-to-potassium ratio at admission may be a potential predictor of prognosis for severe traumatic brain injury. |
| Databáze: | OpenAIRE |
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