Tick transmission of Borrelia burgdorferi to inbred strains of mice induces an antibody response to P39 but not to outer surface protein A

Autor:	William T. Golde, K J Kappel, Y Lobet, C Feron, G Dequesne, C Capiau, D Plainchamp
Jazyk:	angličtina
Rok vydání:	1994
Předmět:	Lipoproteins Immunology Spirochaetaceae Tick Microbiology Mice Lyme disease Ticks Inbred strain Antigen Borrelia burgdorferi Group medicine Animals Borrelia burgdorferi Antigens Bacterial Lyme Disease Mice Inbred BALB C biology biology.organism_classification medicine.disease bacterial infections and mycoses Virology Antibodies Bacterial Mice Inbred C57BL Infectious Diseases Humoral immunity Antigens Surface Bacterial Vaccines bacteria Parasitology Ixodidae Research Article Bacterial Outer Membrane Proteins
Popis:	Natural tick transmission of infection by Borrelia burgdorferi induces a very different serum antibody response than needle inoculation of spirochetes. We present data, obtained by using the mouse model, that show that the OspA response was barely detectable, whereas all animals developed significant anti-P39 titers after exposure to B. burgdorferi-infected ticks.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f624e66fa0139a28cce11f9f56c67a17 https://europepmc.org/articles/PMC186556/ Zobrazit plný text záznamu