The Association between Vitamin D Levels and Urinary Tract Infection in Children
| Autor: | Fatih Üçkardeş, Abdulgani Gülyüz, Aydin Erdemir, Velat Çelik, Habip Almiş, Mehmet Tekin, Capan Konca, Mehmet Turgut, Zelal Kahramaner |
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| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty Endocrinology Diabetes and Metabolism Urinary system Urology vitamin D deficiency Leukocyte Count Sex Factors Endocrinology White blood cell Healthy control medicine Vitamin D and neurology Humans In patient Prospective Studies Risk factor Child Calcifediol Pyelonephritis business.industry Infant Alkaline Phosphatase medicine.disease C-Reactive Protein medicine.anatomical_structure Parathyroid Hormone Child Preschool Urinary Tract Infections Pediatrics Perinatology and Child Health Alkaline phosphatase Female business |
| Zdroj: | Hormone Research in Paediatrics. 83:198-203 |
| ISSN: | 1663-2826 1663-2818 |
| DOI: | 10.1159/000370046 |
| Popis: | Aim: We aimed to examine whether there is any association between serum levels of 25-hydroxyvitamin D [25(OH)D3] and urinary tract infection (UTI) among children. Methods: White blood cell count, serum C-reactive protein, calcium, phosphorus, alkaline phosphatase, parathormone, and serum 25(OH)D3 levels were measured in 82 children experiencing a first episode of UTI, with no risk factors for UTI, and 64 healthy control children. Results: The mean serum levels of 25(OH)D3 among children with UTI were significantly lower than those of controls (11.7 ± 3.3 vs. 27.6 ± 4.7 ng/ml; p < 0.001). The serum levels of 25(OH)D3 were significantly lower in patients with acute pyelonephritis compared to patients with lower UTI (8.6 ± 2.8 vs. 14.2 ± 3.0 ng/ml; p < 0.001). Within the study group, mean serum levels of 25(OH)D3 among girls were lower than those of boys (10.9 ± 3.4 ng/ml vs. 13.2 ± 4.4 ng/ml; p < 0.001). Multivariate analysis showed that a serum 25(OH)D3 level of Conclusions: Our results suggest that vitamin D deficiency may be a risk factor for UTI in children. |
| Databáze: | OpenAIRE |
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