Uveal melanoma survival rates after single dose stereotactic radiosurgery
| Autor: | Adriana Furdova, M Sramka, Robert Furda, G Králik, Pavel Babal, Pavlina Zahorjanova, Karolína Kapitánová, Vladimir Krasnik, D Kobzova |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Adult
Uveal Neoplasms 0301 basic medicine Cancer Research Dose-volume histogram medicine.medical_specialty medicine.medical_treatment Enucleation Radiosurgery Young Adult 03 medical and health sciences 0302 clinical medicine medicine Humans Melanoma Survival rate Aged Retrospective Studies Aged 80 and over business.industry Ciliary body melanoma Retrospective cohort study Middle Aged medicine.disease Survival Rate Treatment Outcome 030104 developmental biology Oncology 030220 oncology & carcinogenesis Female Radiology Complication business |
| Zdroj: | Neoplasma. 65:965-971 |
| ISSN: | 1338-4317 |
| DOI: | 10.4149/neo_2018_171209n808 |
| Popis: | This paper presents the long-term results of single dose stereotactic radiosurgery for intraocular uveal malignant melanoma, and summarizes the results of the retrospective study in 170 Slovak patients. A group of uveal melanoma patients (149 choroidal melanoma, 21 ciliary body melanoma) from 20 to 92 years of age with 59 year median were treated in 2001-2016. There were 81males (47.7%) and 89 females 89 (52.3%). The median overall follow-up time was three years. The median tumor volume at baseline was 0.5 cm³ (ranging from 0.2 to 1.6 cm³). The therapeutic dose was 35.0 Gy by 99% of dose volume histogram. The survival after single dose stereotactic radiosurgery was 96% in one year, 93% in two years, 84% in five years, 80% in seven years and 52% in eleven years. Secondary enucleation was necessary for 22 patients because of secondary glaucoma complication. The enucleation free interval ranged from one to six years. The survival rates in five year intervals and necessity of secondary enucleation due to complications after single dose stereotactic radiosurgery is comparable to other techniques. |
| Databáze: | OpenAIRE |
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