Pelvic plexiform neurofibromatosis presenting with genital numbness
| Autor: | Sachit Shah, Jai Seth, Mahreen Pakzad, Shazia K. Afridi, Lap Yan Leung, Jalesh N. Panicker |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Neurofibromatosis 1 media_common.quotation_subject Orgasm Hypesthesia Plexiform neurofibroma Pathognomonic Scrotum Humans Medicine Neurofibromatosis media_common Neurofibroma Plexiform Neurofibromatosis type I business.industry General Medicine medicine.disease Dermatology Sexual dysfunction medicine.anatomical_structure Genital Neoplasms Male Neurology (clinical) medicine.symptom business Penis |
| Zdroj: | Practical Neurology. 20:165-166 |
| ISSN: | 1474-7766 1474-7758 |
| DOI: | 10.1136/practneurol-2019-002375 |
| Popis: | Neurofibromatosis type I is a common autosomal dominant inherited disorder of neural crest origin, affecting 1 in 3000 people.1 Plexiform neurofibromas, benign peripheral nerve sheath tumours, are considered pathognomonic of neurofibromatosis type I. Pelvic involvement is uncommon and is associated with considerable morbidity.1 A 29-year-old man reported 8 years of progressively increasing left hemiscrotal and gluteal swelling. He had noticed numbness over the penis and scrotum, difficulties with ejaculation and experiencing an orgasm, and perineal pain particularly when trying to ejaculate. He could achieve an erection and had preserved sexual drive, and no bladder or bowel symptoms. He took gabapentin and had never used serotonin-selective reuptake inhibitors. There was no family history of neurofibromatosis type I. General examination was normal with no other cutaneous manifestations of neurofibromatosis type I, suggesting a … |
| Databáze: | OpenAIRE |
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