Surround Integration Organizes a Spatial Map during Active Sensation
| Autor: | Evan H Lyall, Greg I. Telian, Elena Ryapolova-Webb, Hillel Adesnik, Scott R. Pluta |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
sensory map Computer science Surround suppression Population receptive field Sensory system Summation Article Mice 03 medical and health sciences Spatial Processing 0302 clinical medicine Thalamus Sensor array Physical Stimulation Psychology Animals whisker Computer vision education Neurons education.field_of_study Neurology & Neurosurgery active sensation business.industry General Neuroscience Optical Imaging Neurosciences Representation (systemics) Somatosensory Cortex Barrel cortex electrophysiology Electrophysiological Phenomena calcium imaging 030104 developmental biology Touch Receptive field Vibrissae barrel cortex Cognitive Sciences Calcium Artificial intelligence business Neuroscience 030217 neurology & neurosurgery |
| Zdroj: | Neuron, vol 94, iss 6 |
| ISSN: | 0896-6273 |
| DOI: | 10.1016/j.neuron.2017.04.026 |
| Popis: | During active sensation, sensors scan space in order to generate a representation of the outside world. However, since spatial coding in sensory systems is typically addressed by measuring receptive fields in a fixed, sensor-based coordinate frame, the cortical representation of scanned space is poorly understood. To address this question, we probed spatial coding in the rodent whisker system using a combination of two-photon imaging and electrophysiology during active touch. We found that surround whiskers powerfully transform the cortical representation of scanned space. On the single-neuron level, surround input profoundly alters response amplitude and modulates spatial preference in the cortex. On the population level, surround input organizes the spatial preference of neurons intoa continuous map of the space swept out by the whiskers. These data demonstrate how spatial summation over a moving sensor array is critical to generating population codes of sensory space. |
| Databáze: | OpenAIRE |
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