Relationship Between Social Determinants of Health and the Thalassemia Prenatal Diagnosis Test in Zahedan, South Eastern Iran

Autor:	Fahimeh Shahraki, Narjes Sargolzaie, Mostafa Montazer Zohour, Erfan Ayubi
Rok vydání:	2018
Předmět:	Social Determinants of Health Clinical Biochemistry Prenatal diagnosis Iran 030204 cardiovascular system & hematology Logistic regression Odds Consanguinity 03 medical and health sciences 0302 clinical medicine Prenatal Diagnosis mental disorders Odds Ratio Humans Medicine 030212 general & internal medicine Social determinants of health reproductive and urinary physiology Genetics (clinical) Univariate analysis business.industry Biochemistry (medical) Hematology Odds ratio Confidence interval Test (assessment) Case-Control Studies Thalassemia business Demography
Zdroj:	Hemoglobin. 42:231-235
ISSN:	1532-432X 0363-0269
DOI:	10.1080/03630269.2018.1520718
Popis:	Little is known about the social determinants of health (SDH) of taking the prenatal diagnosis (PND) test as a pivotal strategy to prevent occurrences of β-thalasssemia major (β-TM). This study sought to evaluate the relationship between socio-demographic characteristics of parents and taking the PND test at Zahedan, Iran from 2015 to 2016. The design of the present study was a case-control. Data on socio-demographic characteristics of parents including age, education, job, ethnicity, and family relationships, kind of marriage as well as pre marriage test status and PND test status, were obtained from registered medical records. The relationship between socio-demographic characteristics and taking the PND test was evaluated using binary logistic regression. The study included 256 β-thalassemia (β-thal) carrier couples who were referred to the Zahedan Prenatal Diagnosis Center to take the PND test and 47 β-thal carrier couples who already had a newborn with β-TM and had not taken the PND test. Univariate analysis showed that the higher education level of the father, consanguineous parents, official marriages, pre marriage test and consultation, significantly increased the odds of taking the PND test. The significant relationships were not observed in multivariable analysis, however, pre marriage tests and official marriages can be considered as determinants of taking the PND test with odds ratio (OR) [95% confidence interval (95% CI)] of 14.67 (0.64, 334.93) and 3.41 (0.55, 20.94), respectively. Our results provided evidence in which socio-demographic characteristics of the parents may determine their taking the PND test.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f610fe7a5bb9ab203cc8a4ceadcc6331 https://doi.org/10.1080/03630269.2018.1520718 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.