Effect of duodenal osmolality on gastrin and secretin release and on gastric and pancreatic secretion
| Autor: | Janusz S. Swierczek, James C. Thompson, R. Teichmann, Phillip L. Rayford |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
medicine.medical_specialty
Duodenum Secretin Dogs fluids and secretions Glucose Solution Hypertonic Internal medicine Gastrins Animals Medicine Pancreas Gastrin Saline Solution Hypertonic Osmole Meal Gastric Juice business.industry Stomach Osmolar Concentration digestive oral and skin physiology Hypertonic saline Bicarbonates medicine.anatomical_structure Endocrinology Food Tonicity Surgery business |
| Zdroj: | World Journal of Surgery. 3:623-630 |
| ISSN: | 1432-2323 0364-2313 |
| DOI: | 10.1007/bf01654773 |
| Popis: | We have measured the osmolality of duodenal contents in 9 dogs after a hypertonic meal, given either by mouth or directly into the stomach or perfused into the duodenum. A test meal of 2,475 mosm/kg, given by mouth, raised the intraduodenal osmolality to 700–1,500 mosm/kg over a 1-hour period. Hypertonic glucose solutions (2,000 and 3,400 mosm/kg), given into the stomach, were found to be diluted to about 700 and 1,100 mosm/kg, respectively, at the level of the mid-duodenum 30 minutes later. Hypertonic saline solutions (1,800 and 2,700 mosm/kg), perfused into the duodenum, created a stable intraluminal osmolality of 800 and 1,200 mosm/kg, respectively, (about 45% that of the perfusate) after 30 minutes. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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