Prematurity in multiple gestations: identification of patients who are at low risk
| Autor: | Richard K. Silver, Elaine I. Haney, Hope A. Thomas, Mark G. Neerhof, Kimberly S. McMahon, Alan M. Peaceman |
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| Rok vydání: | 2002 |
| Předmět: |
Adult
medicine.medical_specialty Physical examination Gestational Age Cervix Uteri Sensitivity and Specificity Predictive Value of Tests Pregnancy Risk Factors medicine Humans Prospective Studies Pregnancy Complications Infectious Prospective cohort study Cervix Physical Examination Ultrasonography Gynecology Likelihood Functions Fetal fibronectin medicine.diagnostic_test Obstetrics business.industry Infant Newborn Obstetrics and Gynecology Gestational age Vaginosis Bacterial medicine.disease Fetal Blood Fibronectins medicine.anatomical_structure Predictive value of tests Gestation Female Pregnancy Multiple business Infant Premature |
| Zdroj: | American journal of obstetrics and gynecology. 186(6) |
| ISSN: | 0002-9378 |
| Popis: | OBJECTIVE: The purpose of this study was to evaluate a strategy for the identification of patients with multiple gestations who are at low risk for preterm delivery. STUDY DESIGN: A prospective observational study among patients with twin and triplet gestations. At 20 and 24 weeks of gestation, screening for bacterial vaginosis and fetal fibronectin was performed, followed by digital and sonographic assessment of the cervix. The treating physicians were blinded to test results. RESULTS: At the 24-week examination, specificities for delivery at >32 weeks of gestation for digital examination (92.9%), fetal fibronectin level (93.9%), cervical length on sonographic scan (85.1%), and combined fetal fibronectin level and cervical length (81.3%) did not differ statistically. Negative predictive values for these tests were ≥95%. All tests performed better at 24 weeks of gestation than at 20 weeks of gestation. CONCLUSION: At 24 weeks of gestation, a normal digital examination, a negative fetal fibronectin level, a normal cervical length on sonographic scan, or the combination of a negative fetal fibronectin level and a normal cervical length each confer a similarly high likelihood of delivery at >32 weeks of gestation in women with multiple gestations. (Am J Obstet Gynecol 2002;186:1137-41.) |
| Databáze: | OpenAIRE |
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