Study on the regulatory effect of electro-acupuncture on Hegu point (LI4) in cerebral response with functional magnetic resonance imaging

Autor: Xin Zhi, Ling Liu, Wei Wang, Hua Wang, Xiangquan Kong, Dingxi Liu, Jin-bai Huang, Haibo Xu
Rok vydání: 2007
Předmět:
Zdroj: Chinese Journal of Integrative Medicine. 13:10-16
ISSN: 1993-0402
1672-0415
DOI: 10.1007/s11655-007-0010-3
Popis: To study, through blood oxygen level dependent functional magnetic resonance imaging (BOLD fMRI), the cerebral activated areas evoked by electro-acupuncturing (EA) the right Hegu point (LI4) or non-acupoint points on the face, and through comparing their similarities and differences, to speculate on the specific cerebral areas activated by stimulating LI4, for exploring the mechanism of its effect in potential clinical application. EA was applied at volunteers’ right LI4 (of 9 subjects in the LI4 group) and facial non-acupoint points (of 5 subjects in the control group), and whole brain 3-dimensional T1 anatomical imaging of high resolution 1 × 1 × 1 mm3 used was performed with clustered stimulatory mode adopted by BOLD fMRI. Pretreatment and statistical t-test were conducted on the data by SPM2 software, then the statistical parameters were superimposed to the 3-dimensional anatomical imaging. Data from 3 testees of the 9 subjects in the LI4 group were given up eventually because they were unfit to the demand due to different causes such as movement of patients’ location or machinery factors. Statistical analysis showed that signal activation or deactivation was found in multiple cerebral areas in 6 subjects of LI4 group and 5 subjects of the control group (P
Databáze: OpenAIRE
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