Assessment of Fever in African Children: Implication for Malaria Trials
| Autor: | Peter G. Kremsner, Sunny Oyakhirome, Katharina Profanter |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
medicine.medical_specialty
Pediatrics Fever Thermometers Malaria complications Virology medicine Outpatient clinic Humans Protozoal disease Child business.industry Limits of agreement Infant Newborn Skin temperature Infant Articles medicine.disease Infant newborn Surgery Malaria Infectious Diseases El Niño Child Preschool Africa Parasitology business Skin Temperature |
| Popis: | We evaluated methods for assessing body temperature by comparing subjective assessment of fever by parents and doctors with objective axillary, tympanic, and rectal measurements of body temperature in 1000 childrenor = 10-years-old who presented at outpatient clinics with recent history of fever. Sensitivity of subjective assessment of fever were higher at thresholds ofor = 38.3 degrees C with specificity as low as 60%. Axillary methods showed better specificity at fever thresholds of38.0 degrees C with maximum sensitivity of 63% at thresholds ofor = 37.5 degrees C. Bland-Altman analysis showed wide limits of agreement between objective methods of measurements: -1 degrees C to 3 degrees C for comparison of rectal and axillary, -1 degrees C to 2 degrees C for rectal and tympanic, and -1 degrees C to 2 degrees C for tympanic and axillary measurements. A choice of method to measure body temperature for diagnosis of fever in African children should be informed by a trade-off between its specificity and sensitivity that considers thresholds38.0 degrees C. |
| Databáze: | OpenAIRE |
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