Anti-inflammatory secondary metabolites from the stems of Millettia dielsiana Harms ex Diels

Autor:	Bui Thi Thuy Luyen, Le Duc Dat, Hyun Jae Jang, Chu Thi Thanh Huyen, Nguyen Thi Minh Tu, Dang Thi Thu, Tran Thu Huong, Nguyen Van Thong, Young Ho Kim, Nguyen Phuong Thao, Le Huyen Tram, Ngo Viet Duc, Nguyen Duc Hung
Rok vydání:	2019
Předmět:	Lipopolysaccharides Lipopolysaccharide medicine.drug_class Cell Survival Chemical structure Anti-Inflammatory Agents Secondary Metabolism 010402 general chemistry Nitric Oxide 01 natural sciences Biochemistry Anti-inflammatory Millettia Analytical Chemistry Nitric oxide chemistry.chemical_compound Mice medicine Animals Medicinal plants chemistry.chemical_classification Traditional medicine Molecular Structure Plant Stems 010405 organic chemistry Plant Extracts Organic Chemistry Glycoside General Medicine Isoflavones In vitro 0104 chemical sciences RAW 264.7 Cells chemistry Phytochemical
Zdroj:	Carbohydrate research. 484
ISSN:	1873-426X
Popis:	A phytochemical investigation for the constituents of the stems of Millettia dielsiana Harms ex Diels resulted in the isolation of a new isoflavone glycoside, mildiside A (1), and 14 known compounds (2-15). Their chemical structures were determined using a combination of IR, NMR, MS, and optical rotation analysis, as well as comparison with the literature data. The ethanolic (EtOH) extract and several isolated compounds exert the inflammatory effect of nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated murine RAW264.7 macrophage cells.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5fdd19ad359840c4c0de5200e76e291 https://pubmed.ncbi.nlm.nih.gov/31470215 Zobrazit plný text záznamu Full Text from ScienceDirect