New synthesis of PNA-3 ' DNA linker monomers, useful building blocks to obtain PNA/DNA chimeras
| Autor: | Giovanni N. Roviello, Enrico M. Bucci, Roberto Sapio, Carlo Pedone, Margherita Valente, Domenica Musumeci |
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| Přispěvatelé: | Musumeci, D., Roviello, G. N., Valente, M., Sapio, R., Pedone, Carlo, Bucci, E. M., Musumeci, Domenica, Giovanni N., Roviello, Margherita, Valente, Roberto, Sapio, Enrico M., Bucci |
| Jazyk: | angličtina |
| Rok vydání: | 2004 |
| Předmět: |
Magnetic Resonance Spectroscopy
Recombinant Fusion Proteins Biophysics Biochemistry Biomaterials chemistry.chemical_compound PNA/DNA chimera mental disorders Methods monomethoxytrityl group peptide nucleic acids Molecular Structure Chemistry musculoskeletal neural and ocular physiology PNA–DNA linker Organic Chemistry DNA General Medicine Combinatorial chemistry Monomer PNA-DNA linker biological sciences cardiovascular system peptide nucleic acid Linker tissues |
| Zdroj: | Biopolymers 76 (2004): 535–542. doi:10.1002/bip.20135 info:cnr-pdr/source/autori:Musumeci, D.; Roviello, G.N.; Valente, M.; Sapio, R.; Pedone, C.; Bucci, E.M./titolo:New synthesis of PNA-3 ' DNA linker monomers, useful building blocks to obtain PNA%2FDNA chimeras/doi:10.1002%2Fbip.20135/rivista:Biopolymers (Print)/anno:2004/pagina_da:535/pagina_a:542/intervallo_pagine:535–542/volume:76 info:cnr-pdr/source/autori:Domenica Musumeci; Giovanni N Roviello; Margherita Valente; Roberto Sapio; Carlo Pedone; Enrico M Bucci/titolo:New synthesis of PNA-3? DNA linker monomers, useful building blocks to obtain PNA%2FDNA chimeras/doi:10.1002%2Fbip.20135/rivista:Biopolymers (Print)/anno:2004/pagina_da:535/pagina_a:542/intervallo_pagine:535–542/volume:76 |
| DOI: | 10.1002/bip.20135 |
| Popis: | A new synthetic strategy to get the PNA-3? DNA linker with the monomethoxytrityl (Mmt) group as temporary protection of the backbone to be used for the synthesis of PNA/DNA chimeras was employed and a convenient strategy to obtain Mmt PNA monomers was developed. The synthetic strategies take advantage of the introduction of the acid-labile Mmt- protecting group in the first step. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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