The morphology of corneal endothelial cells in long term soft contact lens wearers in Kuala Lumpur
| Autor: | Low Yu Chen, Bariah Mohd-Ali |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Corneal endothelium Time Factors Visual acuity genetic structures Cell Count Slit Lamp Microscopy Young Adult 03 medical and health sciences 0302 clinical medicine Ophthalmology medicine Humans Snellen chart Retrospective Studies Kuala lumpur business.industry Endothelium Corneal Malaysia Gender distribution Endothelial Cells General Medicine Corneal Endothelial Cell Loss Contact Lenses Hydrophilic Subjective refraction eye diseases Endothelial cell density Contact lens 030221 ophthalmology & optometry Female sense organs medicine.symptom business 030217 neurology & neurosurgery Optometry |
| Zdroj: | Contact Lens and Anterior Eye. 44:72-75 |
| ISSN: | 1367-0484 |
| DOI: | 10.1016/j.clae.2020.06.007 |
| Popis: | To analyse and compare the alterations in corneal endothelium morphology induced by different materials and durations of wearing soft contact lenses (CL) among young adults living in Kuala Lumpur.Healthy soft CL wearers were invited to participate in this study. Visual acuity (VA) was measured using the Snellen chart, and subjective refraction was performed using cross-cylinder technique. Standard ocular assessments were conducted using a slit lamp biomicroscope and morphology of corneal endothelial cells (endothelial cell density, ECD, coefficient variation, COV, hexagonality, HEX and central corneal thickness, CCT) were evaluated using a non-contact specular microscope. Statistical analysis was conducted using ANOVA and data from the right eye only is included.A total of 72 subjects (32 SiHy and 40 HCL wearers) and 24 non-CL wearers (control) participated in this study. The gender distribution for study subjects was 13 males and 59 females, with a mean age 22.15 ± 1.84 years old. The mean refraction was -1.86 ± 1.25DS. The duration of wearing CL ranged from 1 to 9 years. Subjects were later divided into 2 groups following duration of CL wear: Group 1 (5 years) and Group 2 (≥5 years) for analysis purposes. Statistical analysis showed significant alterations in ECD, COV and HEX of CL wearers (p 0.05), with more changes found in HCL and Group 2 wearers. No significant change was found in CCT.This study concludes that soft CL wear induced alterations in the morphology of corneal endothelial cells. Contact lens material and duration of CL wear (in years) are factors that affect the alterations. Optometrists are recommended to regularly evaluate the morphology of corneal endothelial cells in CL wearers and provide necessary intervention when required. |
| Databáze: | OpenAIRE |
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