Possibly Late-Onset Arrhythmogenic Right Ventricular Cardiomyopathy: Unique Triglyceride Deposition by Analysis of Lipid Contents
| Autor: | Hirofumi Aoki, Kouji Kajinami, Akihiro Shioya, Kentaro Yamamoto, Motona Kumagai, Yoshihiko Ikeda, Kenichi Mizutani, Toshie Terauchi, Xin Guo, Nozomu Kurose, Sohsuke Yamada, Satoko Nakada |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
lipid analysis Pleural effusion 030232 urology & nephrology Case Report Late onset 030204 cardiovascular system & hematology Right ventricular cardiomyopathy 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Lymphoplasmacytic Infiltrate Internal medicine Ascites medicine Pathological lcsh:R5-920 Triglyceride business.industry arrhythmogenic right ventricular cardiomyopathy (ARVC) Cardiac muscle General Medicine medicine.disease triglyceride (TG) medicine.anatomical_structure chemistry Cardiology medicine.symptom business lcsh:Medicine (General) |
| Zdroj: | Clinical Medicine Insights: Case Reports, Vol 12 (2019) Clinical Medicine Insights. Case Reports |
| ISSN: | 1179-5476 |
| Popis: | We presented an unusual arrhythmogenic right ventricular cardiomyopathy (ARVC) case of a late-60s elderly man’s death, due to severe pericardial/pleural effusion and ascites, and arrhythmic events, with unique pathological features. The hypertrophic heart grossly displayed yellowish to yellow-whitish predominantly in the variably thinned wall of the dilated right ventricle. Microscopic findings showed diffuse fatty/fibrofatty replacement in not only the right but left ventricular myocardium, together with an outer lymphoplasmacytic infiltrate. According to the lipid contents analysis, the triglyceride content, but not the cholesterol content, in our patient’s right and left ventricular cardiac muscle was much higher than that in the control subject. We propose that this unique triglyceride deposition in our possibly late-onset ARVC case might be one of new clues to understand its enigmatic cause. Further prospective studies are needed to validate the presence and significance of a greater volume of triglyceride deposit, after collecting and investigating a larger number of early and late-onset ARVC cases examined. |
| Databáze: | OpenAIRE |
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