Effectiveness of butorphanol as an adjuvant to lidocaine for haematoma or periosteal block: A prospective, randomised, double blind study
| Autor: | Sunil Chiruvella, Nawaz Ahmed Shaik, Surisetty Sreenivasa Rao, Manduri Sreenivasa Rao, Siddareddigari Velayudha Reddy |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
closed fracture reduction Lidocaine Visual analogue scale business.industry Butorphanol Sedation Analgesic Block (permutation group theory) periosteal block Surgery haematoma block Clinical trial lcsh:RD78.3-87.3 Exact test Anesthesiology and Pain Medicine lcsh:Anesthesiology Anesthesia medicine Clinical Investigation medicine.symptom business medicine.drug |
| Zdroj: | Indian Journal of Anaesthesia, Vol 57, Iss 2, Pp 150-155 (2013) Indian Journal of Anaesthesia |
| ISSN: | 0019-5049 |
| Popis: | Background: The peripheral nerve endings carrying pain contains opiod receptors. Blocking these receptors during haematoma block or periosteal block may provide better analgesia. Aim: Evaluation of effectiveness and safety of butorphanol as an adjuvant to lidocaine for haematoma block. Settings and Design: This is a two centre, prospective, individually randomised, two group, parallel, double-blind clinical trial. Methods: In this study, 115 American society of anaesthesiologist grade I and II adult patients scheduled for closed reduction of fractures were randomly allocated into two groups; Group A received 1% lidocaine (2 mg/kg) where as Group B received 1% lidocaine (2 mg/kg) with butorphanol (0.02 mg/kg) during haematoma block. Pain was assessed before, during and after manipulation of fracture by using visual analogue scale (VAS 0-10). Onset time of block, time for first rescue analgesic, 24 hour analgesic requirement and sedation levels were noted. Statistical Analysis: Data analysed with the unpaired t-test with Welch correction assuming unequal variances and Fisher′s exact test using Graph pad Prism 5.02 version. Results: Onset time of haematoma block was significantly less in the butorphanol group compared to the lidocaine group ( P=0.0003). The mean time for first rescue analgesic was significantly higher and total analgesic requirement was significantly lower in the butorphanol group ( P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|