Adverse Effects of Atropine on the Sinus Node in Familial Amyloid Polyneuropathy
| Autor: | Yoichi Hokamura, Toru Okajima, Yoshiaki Matsumoto, Haruhiko Tokuomi, Tadahiro Ono, Yutaka Horio |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
Adult
Atropine Male Pulmonary and Respiratory Medicine Bradycardia Critical Care and Intensive Care Medicine medicine Humans Paresthesia Adverse effect Cycle length Sinus (anatomy) Sinoatrial Node business.industry Sinoatrial node Amyloidosis Syndrome medicine.disease medicine.anatomical_structure Anesthesia Heart Function Tests Amyloid polyneuropathy medicine.symptom Cardiology and Cardiovascular Medicine business medicine.drug |
| Zdroj: | Chest. 82:190-192 |
| ISSN: | 0012-3692 |
| DOI: | 10.1378/chest.82.2.190 |
| Popis: | Electrophysiologic studies were performed in a 33-year-old man with familial amyloid polyneuropathy (FAP) before and after administration of atropine, 1 mg intravenously. Atropine induced prolongation of the sinus node cycle length, sinoatrial conduction time, and sinus nodal recovery time. These findings indicate that the therapeutic doses of atropine may be useless or potentially detrimental for bradyarrhythmias or sinoatrial conduction disturbances in some patients with FAP. |
| Databáze: | OpenAIRE |
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