The Effect of Pecan Oil on Hippocampal Cells Apoptosis of Ovariectomized Rats
| Autor: | Xing-yu Zhao, Shijie Lv, Kuang Ren, Anheng Liu, Wei Zhang |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
Antioxidant Materials science medicine.medical_treatment Unsaturated fat Apoptosis Hippocampal cell General Medicine Hippocampal formation medicine.disease_cause chemistry.chemical_compound Endocrinology Mechanism of action chemistry Biochemistry Internal medicine medicine Ovariectomized rat medicine.symptom Ovariectomized rats Pecan oil Engineering(all) Oxidative stress |
| Zdroj: | Procedia Engineering. 18:375-380 |
| ISSN: | 1877-7058 |
| DOI: | 10.1016/j.proeng.2011.11.060 |
| Popis: | Pecan oil is an edible pressed oil extracted from the pecan nut; it contains approximately 90% unsaturated fat. Previous study showed that unsaturated faty had potent antioxidant activity. Oxidative stress is a pathological change which is higher in postmenopausal women. In the present study, we reported the apoptosis inhibition of hippocampal cells by pecan oil in ovariectomized rats. And the results showed that the pecan oil has protective effect on hippocampal cell apoptosis induced by ovariectomized operation. The mechanism of action could be related to enhancement of the antioxidant activity and adjustment of Caspase-3 expression. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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