Prelimbic proBDNF Facilitates Retrieval-Dependent Fear Memory Destabilization by Regulation of Synaptic and Neural Functions in Juvenile Rats
Autor: | Wei Sun, Xiao Chen, Yazi Mei, Yang Yang, Xiaoliang Li, Lei An |
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Rok vydání: | 2022 |
Předmět: | |
Zdroj: | Molecular neurobiology. 59(7) |
ISSN: | 1559-1182 |
Popis: | Fear regulation changes as a function of the early life is a key developmental period for the continued maturation of fear neural circuitry. The mechanisms of fear retrieval-induced reconsolidation have been investigated but remain poorly understood. The involvement of prelimbic proBDNF in fear memory extinction and its mediated signaling have been reported previously. Specifically, blocking the proBDNF/p75 |
Databáze: | OpenAIRE |
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