Ammonium acetate as a novel buffer for highly selective robust urinary HPLC-ICP-MS arsenic speciation methodology
| Autor: | Pablo Fernandez Rodriguez, J.L. López Colón, R.M. Martín-Aranda, J.H. de Mendoza |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
media_common.quotation_subject
chemistry.chemical_element 02 engineering and technology Acetates 01 natural sciences Arsenicals Mass Spectrometry Arsenic Analytical Chemistry chemistry.chemical_compound Ammonium Chromatography High Pressure Liquid media_common Chromatography Chemistry 010401 analytical chemistry Arsenic speciation Repeatability 021001 nanoscience & nanotechnology Highly selective 0104 chemical sciences Speciation 0210 nano-technology Ammonium acetate Hplc icp ms |
| Zdroj: | Talanta. 221:121494 |
| ISSN: | 0039-9140 |
| Popis: | Ammonium acetate is employed in order to develop a novel HPLC-ICP-MS arsenic speciation methodology applicable to six arsenic species, i.e, AC, AB, AsIII, AsV, DMA and MMA. The most predominant species in the toxicological field are covered in a 30-min chromatogram with reproducible and repeatability peak area ratio. Moreover, typical problems from traditional methods are sorted out by using a robust, high-selective and 75ArCl+ interference-free methodology. Chromatographic and detector optimization ensures low LOQs for each species with acceptable precision and accuracy values obtained using four urinary arsenic speciation PTS enabling to be useful for sub ng mL-1 arsenic exposure assessments. |
| Databáze: | OpenAIRE |
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