Absorption, distribution, and excretion of ethylmercuric chloride

Autor: A.C. Jerstad, Elizabeth Csonka, V. L. Miller, P.A. Klavano
Rok vydání: 1961
Předmět:
Zdroj: Toxicology and Applied Pharmacology. 3:459-468
ISSN: 0041-008X
DOI: 10.1016/0041-008x(61)90061-8
Popis: Ethylmercuric chloride was given to chicks and rats intramuscularly and orally. The compound is apparently absorbed unchanged. Metabolism of ethylmercury is much slower than of phenylmercury. Intact ethylmercury is detectable in the liver and kidneys for 21 days after dosing. The ethylmercury is present to a much greater extent in the chick liver than in the kidney, whereas in the rat, the ethylmercury is predominantly in the kidney and blood.
Databáze: OpenAIRE