Short‐ and long‐term outcome following thoracoamniotic shunting for fetal hydrothorax
| Autor: | David Chitayat, Gareth Seaward, T. Van Mieghem, Xiang Y. Ye, Johannes Keunen, Greg Ryan, Edmond Kelly, Rory Windrim, Nimrah Abbasi |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male Pediatrics medicine.medical_specialty Hydrothorax Gestational Age Thoracostomy Obstetrics and gynaecology Pregnancy Intensive care Humans Medicine Radiology Nuclear Medicine and imaging Amnion Survival rate Retrospective Studies Fetal Therapies Fetus Radiological and Ultrasound Technology business.industry Infant Newborn Pregnancy Outcome Infant Obstetrics and Gynecology Gestational age General Medicine medicine.disease Survival Rate Fetal Diseases Treatment Outcome Reproductive Medicine Child Preschool Cohort Female business |
| Zdroj: | Ultrasound in Obstetrics & Gynecology. 57:624-630 |
| ISSN: | 1469-0705 0960-7692 |
| Popis: | OBJECTIVES To assess short- and long-term outcome in a cohort of fetuses diagnosed with hydrothorax (FHT) which underwent thoracoamniotic shunting in utero, and to examine the antenatal predictors of survival and of survival with normal neurodevelopmental outcome. METHODS This was a retrospective analysis of 132 fetuses that underwent thoracoamniotic shunting at our center between 1991 and 2014. Data were extracted from hospital obstetric and relevant neonatal intensive care and neonatal developmental follow-up databases. Outcomes included survival to discharge and survival with normal neurodevelopmental outcome beyond 18 months. Information on malformations, syndromes and genetic abnormalities were obtained from antenatal, postnatal and pediatric hospital records or by parent report. We compared pregnancy characteristics among those who survived vs non-survivors and among those with normal neurodevelopmental outcome vs those who were abnormal or died. We explored whether there was a trend in survival over the study period. RESULTS The mean gestational age at diagnosis of FHT was 25.6 weeks. The fetus was hydropic at diagnosis in 61% of cases, 69% had bilateral effusions and 55% had bilateral shunts inserted. Other diagnoses were present in 24% of cases, two-thirds of which were discovered only postnatally. There were 16 intrauterine and 30 neonatal deaths, with a 65% survival rate overall. The mean gestational age at delivery of liveborns was 35.4 (range, 26.9-41.6) weeks, and 88/116 (76%) were preterm ( |
| Databáze: | OpenAIRE |
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