Synthesis, photophysical and photobiological characterization of BSA nanoparticles loaded with chloroaluminium phthalocyanine by one-step desolvation technique for photodynamic therapy action

Autor:	Janicy Arantes Carvalho, Milton Beltrame Junior, Andreza Ribeiro Simioni, Agnes Cecheto Trindade, Alexandro da Silva Abreu
Rok vydání:	2019
Předmět:	Indoles Cell Survival medicine.medical_treatment 0206 medical engineering Biomedical Engineering Biophysics Nanoparticle Bioengineering Photodynamic therapy One-Step 02 engineering and technology Isoindoles Biomaterials chemistry.chemical_compound medicine Acetone Organometallic Compounds Humans Bovine serum albumin Drug Carriers Ethanol Photosensitizing Agents biology Macrophages Serum Albumin Bovine 021001 nanoscience & nanotechnology 020601 biomedical engineering Combinatorial chemistry chemistry Photochemotherapy biology.protein Phthalocyanine Nanoparticles Glutaraldehyde 0210 nano-technology
Zdroj:	Journal of biomaterials science. Polymer edition. 30(16)
ISSN:	1568-5624
Popis:	This work describes the preparation of bovine serum albumin (BSA) nanoparticles by one-step desolvation method using acetone/ethanol as precipitating agent, glutaraldehyde as crosslinking agent, sodium azide as a preservative and water as reaction media for chloroaluminium phthalocyanine (ClAlPc) incorporation for photodynamic therapy action. The characterization of the nanoparticulate system was carried out using steady-state technique, scanning electron microscopy study and their biological activity was evaluated using
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5cf88a5a3946c096f29e8f95b5f2474 https://pubmed.ncbi.nlm.nih.gov/31354067 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.